That said, it's important to recognize that locking in itself is not bad. It does, in fact, serve an important purpose to ensure that applications properly and orderly consume or produce data. The key challenge is with the original manual implementation of it using APIs like getReader() and releaseLock(). With the arrival of automatic lock and reader management with async iterables, dealing with locks from the users point of view became a lot easier.
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The efficiency depends on the query size relative to the data distribution. A small query in a sparse region prunes almost everything. A query that covers the whole space prunes nothing (because every node overlaps), degenerating to a brute-force scan. The quadtree gives you the most benefit when your queries are spatially local, which is exactly the common case for map applications, game physics, and spatial databases.